WebApr 1, 2010 · Cocaine induced vasospasm is alpha receptor mediated and is Screening for cocaine Cocaine use should always be considered in young to middle-aged patients who present with atypical chest pain. Considering the fact that not many would be forthcoming about the use of cocaine, it would be prudent to perform a toxicology screen. WebFeb 5, 2014 · Cocaine may induce myocardial ischemia through various mechanisms, including coronary vasospasm, platelet aggregation within the coronary arteries, as well as rupture of an atherosclerotic plaque. At the molecular level, cocaine induces coronary vasospasm via inhibition of norepinephrine reuptake by presynaptic neurons.
Influence of Redox and Dopamine Regulation in Cocaine-Induced ...
WebSep 1, 2015 · Cocaine induced chest pain Unopposed alpha effect 1. Introduction Cocaine is one of the most common drugs found in patients who seek EHC. In 2006, six million Americans aged 12 and older had abused cocaine in some form [1]. Cocaine is a potent vasoconstrictor ( [2], [3], [4], Blaho, Merigian et al. 1996, Chang, Walsh et al. 2011). WebAt a 20 °C ambient temperature, cocaine (10–40 mg/kg, i.p.) induced a dose-dependent fall in body temperature, while a dose of cocaine (20 mg/kg, i.p.) at a 35 °C ambient temperature caused a small increase (about 0.6 °C) in core body temperature in conscious rats . Ferguson et al. demonstrated that injection of dopamine (20 ug) into the ... britt chocolates supermarket ny
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WebCocaine is a potent sympathomimetic drug usually associated with cardiotoxicity, including ventricular arrhythmia, systemic hypertension and acute myocardial infarction. It … Web8. List 3 pathophysiologic effects of cocaine-induced MI 9. What is the approach to ACS management in patients using cocaine? 10. Name five sympathomimetic drugs other than cocaine 11. List the 8 severe complications of sympathomimetics 12. Compare body packers to body stuffers 13. What are the primary risks with MDMA and … WebCocaine blocks the reuptake of norepinephrine and dopamine at the presynaptic adrenergic terminals, causing an accumulation of catecholamines at the postsynaptic receptor and thus acting as a powerful sympathomimetic agent. 10,11 Cocaine causes increased heart … britt chiropractic dawson springs ky