Erh gene and its role in cancer cells
WebDec 10, 2012 · Here, we identify the evolutionarily conserved gene enhancer of rudimentary homolog (ERH), in which depletion causes greater toxicity in cancer cells with mutations … WebMay 15, 2024 · The IPA® and Metascape® pathway analyses showed that the ERH gene may affect proliferation and apoptosis by affecting the apoptosis, cell cycle, Toll-like receptor (TLR), NF-κB or TGF-beta signalling pathways. Upstream analysis determined that the ERH gene may regulate TNF and NK-κB in the BC T24 cell lines.
Erh gene and its role in cancer cells
Did you know?
WebJun 14, 2024 · BackgroundThere is a lack of research on the molecular interaction of the enhancers of rudimentary homolog (ERH) in bladder cancer (BC) cells. This study aimed to determine the interacting proteins of ERH in human T24 cells.MethodsFirst, the ERH gene was overexpressed in human T24 cells. Coimmunoprecipitation (co-IP) and shotgun … WebApr 10, 2024 · The alpha-thalassemia mental retardation X-linked (ATRX) syndrome protein is a chromatin remodeling protein that primarily promotes the deposit of H3.3 histone variants in the telomere area. ATRX mutations not only cause ATRX syndrome but also influence development and promote cancer. The primary molecular characteristics of …
WebTable S1. 103 Ferroptosis-Related Genes Retrieved from the Genecards; Host Protein Interactions; The Enigmatic ERH Protein: Its Role in Cell Cycle, RNA Splicing and Cancer; Original Article ERH Is Up-Regulated in Bladder Cancer and Regulates the Proliferation and Apoptosis of T24 Bladder Cancer Cells WebHochschulschriften online nicht zugänglich. Lohmüller, Michael: Exploiting genome-wide CRISPR/Cas9 loss-of-function screens to identify novel regulators of miRNA biogenesis. Innsbruck, 2024
WebFunctional complementation screens can identify known or novel proteins with important intracellular activities. We have isolated human enhancer of filamentation 2 (HEF2) in a screen to find human ge... WebJul 23, 2024 · While a cell’s genome contains all of its genetic material, the epigenome plays a critical role in determining which of these genes will be expressed. Every cell’s genome has epigenomic modifications — proteins and chemical compounds that attach to DNA but do not alter its sequence. These modifications, which vary by cell type, …
WebEnhancer of rudimentary homolog (ERH) is a small, highly conserved protein among eukaryotes. Since its discovery nearly 20 years ago, its molecular function has remained …
WebApr 14, 2024 · Recurrence-associated genes involved in dendritic cell differentiation. To identify potential prognostic candidates for thyroid cancer, we used a list of genes from the Gene Ontology (GO) term “dendritic cell differentiation” (GO:0097028) [].The effects of gene expression for each gene on disease recurrence were analyzed using Cox regression … ion red colorsWeban essential role in cell proliferation, survival, cycle progression and apoptosis [16] . Based on the PPI network, we identified 10 hub genes, including MYC, CDH1, VEGFA, CD24, CXCR4, CXCL12, ACOX1, ACSL1, ACACA and SCD.MYC gene belongs to a group of classical oncogenes, including c-MYC, n-MYC and l-MYC [17] , and encodes a nuclear … ion red shampooWebSep 29, 2024 · Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro-apoptotic and antiproliferative functions, IFN-γ is considered potentially useful for adjuvant immunotherapy for different types of cancer. Moreover, it IFN-γ may inhibit angiogenesis … on the ekman layer in a circular vortexWebHistone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was … on the elastic stiffness of grain boundariesWebSep 14, 2024 · Liquid biopsy provides real-time monitoring of tumor evolution and response to therapy through analysis of circulating tumor cells (CTCs) and plasma-circulating … ion rechargeable batteriesWebApr 13, 2024 · The results showed that SCNAs of BUB1B reduced immune cell enrichment in the aforementioned cancer types (Fig. 5), especially in STAD, indicating a clear link between BUB1B genetic alteration and ... on the electrode surfaceWebMar 12, 2024 · ERH is also necessary for the survival of cancer cells with KRAS mutation (Weng et al. 2012), indicating its role in enhancing cancer cell growth and metastasis. ... ion redline weight