WebThe ASGPR – a type II transmembrane glycoprotein also known as hepatic lectin – is the only liver-specific autoantigen to be identified thus far. It was described in an attempt to identify possible autoantigenic targets expressed on hepatocytes in AIH and is a component of the crude liver extract preparation known as LSP. Web1 apr. 2024 · The complement system is the most important part of the innate immune system which is activated by classical, alternative and lectin pathways. It consists of more than 40 membrane and soluble proteins, including plasma complement components, soluble or membrane-type complement regulatory proteins and complement receptors (Figure 1 ).
Binding of Synthetic Oligosaccharides to the Hepatic Gal/GalNAc Lectin
Web8 aug. 2024 · Primary hepatocytes and HSCs were isolated, and human hepatic LO2 and stellate LX2 cells were used. Small extracellular vesicles (EVs) were purified, and key proteins were identified. ARRB1 was up-regulated in hepatocytes and associated with autophagic blockage in liver fibrosis. Webwhen hepatic lectins were blocked with competitive glycoeonjugates, tumor cell colonization of the liver could be prevented in two different model systems. Introduction In many tumor systems lung and liver are the organs most frequently involved in the formation of secondary tumor colonies. fast math website
Facile Synthesis of a High-Affinity Ligand for Mammalian Hepatic …
Weblectin (1). A similar trend was reported for the isolated human hepatic lectin using asialobi- and asialotriantennary glycopep- tides in which the Ki values were 3.9 X and 1 X M, D. T. Connolly, R. Townsend, K. Kawaguchi, M. K. Hobish, W. R. Bell, and Y. C. Lee, manuscript in … WebWe surveyed the calcium-requiring (C-type) lectins in alligator liver. The major lectin purified by affinity chromatography was termed alligator hepatic lectin (AHL) and was found to be specific for mannose/L-fucose. AHL contained approximately equal amounts of 21- and 23-kDa bands upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis. WebBinding characteristics of N-acetylglucosamine-specific lectin of the isolated chicken hepatocytes: similarities to mammalian hepatic galactose/N-acetylgalactosamine-specific lectin. Biochemistry 1989, 28 (21) , 8351-8358. french open women\u0027s draw