Hyaluronan and proteoglycan link protein
Web13 dec. 2024 · Colorectal cancer (CRC) is the third most common diagnosed cancer worldwide, but there are no effective cures for it. Hyaluronan and proteoglycan link protein-1 (HAPLN1) is a component of the ... Web4 feb. 2024 · Hyaluronan and proteoglycan link protein 1 (HAPLN1), also named cartilage link protein 1 (Crtl-1), is a 354-amino acid glycoprotein and an essential …
Hyaluronan and proteoglycan link protein
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Web17 nov. 2024 · Hyaluronan Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Promotes Viability of Rheumatoid Arthritis Fibroblast-Like Synoviocytes November 2024 DOI: License CC BY 4.0 Authors: Yong Chen... Web4 feb. 2024 · Osteoblast regeneration, characterized by osteoblast differentiation, is the basis of fracture healing and accelerates fracture repair. It has been reported that …
WebBekku et al. (2003) cloned mouse and human HAPLN4, which they termed BRAL2. The deduced mouse protein contains 400 amino acids and has a typical signal peptide … Web12950 Ensembl ENSG00000145681 ENSMUSG00000021613 UniProt P10915 Q9QUP5 RefSeq (mRNA) NM_001884 NM_013500 RefSeq (protein) NP_001875 NP_038528 Location (UCSC) Chr 5: 83.64 – 83.72 Mb Chr 13: 89.69 – 89.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Hyaluronan and proteoglycan link …
WebA glycoprotein is a compound containing carbohydrate (or glycan) covalently linked to protein. The carbohydrate may be in the form of a monosaccharide, disaccharide (s), oligosaccharide (s), polysaccharide (s), or their derivatives (e.g. sulfo- or phospho-substituted). One, a few, or many carbohydrate units may be present. WebThe hyaluronan and proteoglycanbinding link protein (Hapln) is a key molecule in the formation and control of hyaluronan-based condensed perineuronal matrix in the …
Web1 jan. 2016 · Exposure to RELM-β increased TGF-β1, TGF-β2, collagen I, fibronectin, smooth muscle α-actin, laminin α1, and hyaluronan and proteoglycan link protein 1 (Hapl1) production as well as ...
Web8 dec. 2024 · HAPLN3 hyaluronan and proteoglycan link protein 3 Gene ID: 145864, updated on 12-Aug-2024 Gene type: protein coding Also known as: EXLD1; HsT19883 … scotland run park williamstown njWebVandaag · Core protein linkage regions for synthesis and polymerization of CS and KS on the aggrecan core protein domains are illustrated in Fig. 1.2.CS is O-glycosidically … scotland run wedding pricesWebHyaluronan and proteoglycan link protein 1 Alternative names Cartilage-linking protein 1 ( Cartilage-link protein) Proteoglycan link protein Gene names Name HAPLN1 … scotland run park summer campWebThe link proteins. Aggregates of chondroitin-keratan sulfate proteoglycan (aggrecan) and hyaluronic acid (hyaluronan) are the major space-filling components of cartilage. A … scotland run golf course weddingWeb6 jun. 2003 · In human, only three classes were identified, and were designated HAPLN (hyaluronan and proteoglycan link protein) 1–3, where CRTL1 was redesignated HAPLN1. One of the new HAPLN genes, HAPLN2, has subsequently been reported elsewhere as Brain Link Protein 1, BRAL1 (10). premier health xray springboro ohioWebAll HAPLN genes were linked and colocalized with 1 of 4 large aggregating chondroitin sulfate proteoglycan (CSPG) genes in the human genome, and each linked pair was … premier hearing solutionsWebCartilage link protein stabilizes aggregates of aggrecan and hyaluronan, giving cartilage its tensile strength and elasticity. Cartilage provides the template for endochondral ossification and is crucial for determining the length and width of the skeleton. During endochondral bone formation, hypertrophic chondrocytes die and the cartilage is ... premier hearing corpus